Sources of Genetic Variation

NGSS HS-LS3-2: Make and defend a claim based on evidence that inheritable genetic variations may result from: (1) new genetic combinations through meiosis, (2) viable errors occurring during replication, and/or (3) mutations caused by environmental factors.

Total Novel Genetic Variations Generated:

Gather evidence from the three mechanisms below.

0

1. Meiosis (Crossing Over)

During sperm/egg creation, homologous chromosomes pair up and swap sections, creating entirely new combinations of alleles.

Click segments to swap

A
B
C
D
a
b
c
d
New Combinations: 0

2. DNA Replication Errors

Before a cell divides, it must copy billions of DNA bases. The machinery is highly accurate, but rare random mistakes (point mutations) happen.

Original Template Strand:
New Copied Strand:
Replication Errors: 0

3. Environmental Mutations

External factors like UV radiation or chemicals can physically damage DNA, causing mutations that, if in gametes, are inherited.

Click cell to irradiate (UV)

Radiation Mutations: 0