Science Task Prescreen

Task Title: Protein Unfolding & Denaturation

Grade: High School

Date: 2023-10-26

SEP: Constructing Explanations and Designing Solutions

DCI: LS1.A: Structure and Function

CCC: Structure and Function

Task Purpose: To gather evidence using a simulation on how extreme temperatures and pH changes cause a protein (hemoglobin) to lose its 3D structure and function, and construct an explanation linking this to real-world phenomena like high fevers.

Instructions

Prescreen Questionnaire

Question Yes No
1. Is there a phenomenon or problem driving the task? [x] [ ] 🚩
2. Can the majority of the task be answered without using information provided by the task scenario? [ ] 🚩 [x]
3. Can significant portions of the task be answered successfully by using rote knowledge (e.g., definitions, prescriptive or memorized procedure)? [ ] 🚩 [x]
4. Does the majority of the task require students to use reasoning to successfully complete the task? [x] [ ] 🚩
5. Does the task require students to use some understanding of disciplinary core ideas to successfully complete the task? [x] [ ] 🚩
6. Do students have to use at least one science and engineering practice to successfully complete the task? [x] [ ] 🚩
7. Are the dimensions assessed separately in the majority of the task? [ ] 🚩 [x]
8. Is the task coherent and comprehensible from the student perspective? [x] [ ] 🚩

Recommendation

Based on your assessment needs and the task purpose recorded above, make a recommendation about this task moving forward (choose one):

Summary

Summarize your evidence and reasoning:

This task passes the prescreener. It successfully anchors learning in an engaging biological phenomenon and integrates the three dimensions by having students observe structural changes in a protein model to explain loss of function.